Anti-allergic Effect of Acteoside Derived from Arid Land Plant Cistanche tubulosa
نویسندگان
چکیده
The immediate-type allergic reaction is involved in many allergic diseases such as asthma, allergic rhinitis, and sinusitis. The discovery of drugs for the treatment of immediate-type allergic disease is a very important subject in human health. The three kinds of phenylethanoid glycoside, acteoside, echinacoside and cistanoside A, were extracted from Cistanche tubulosa which thrives in arid land. In this report, we investigated the effect of acteoside, echinacoside and cistanoside A on the immediate-type allergic reaction, focusing on the basophilic cell-mediated allergic reaction. Acteoside, echinacoside and cistanoside A decreased β-hexosaminidase release from IgE-sensitized BSA-stimulated RBL-2H3 cells at the antigen–antibody binding stage.
منابع مشابه
Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells.
The immediate-type allergic reaction is involved in many allergic diseases such as asthma, allergic rhinitis, and sinusitis. In this study, we investigated the effect of acteoside extracted from CISTANCHE TUBULOSA (Schrenk) R. Wight on the basophilic cell-mediated allergic reaction. The effect of acteoside on β-hexosaminidase release and intracellular [Ca (2+)] I level from rat basophilic leuke...
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